San Diego
Improving Drug Identification in Overdose Death Surveillance using Large Language Models
Funnell, Arthur J., Petousis, Panayiotis, Harel-Canada, Fabrice, Romero, Ruby, Bui, Alex A. T., Koncsol, Adam, Chaturvedi, Hritika, Shover, Chelsea, Goodman-Meza, David
The rising rate of drug-related deaths in the United States, largely driven by fentanyl, requires timely and accurate surveillance. However, critical overdose data are often buried in free-text coroner reports, leading to delays and information loss when coded into ICD (International Classification of Disease)-10 classifications. Natural language processing (NLP) models may automate and enhance overdose surveillance, but prior applications have been limited. A dataset of 35,433 death records from multiple U.S. jurisdictions in 2020 was used for model training and internal testing. External validation was conducted using a novel separate dataset of 3,335 records from 2023-2024. Multiple NLP approaches were evaluated for classifying specific drug involvement from unstructured death certificate text. These included traditional single- and multi-label classifiers, as well as fine-tuned encoder-only language models such as Bidirectional Encoder Representations from Transformers (BERT) and BioClinicalBERT, and contemporary decoder-only large language models such as Qwen 3 and Llama 3. Model performance was assessed using macro-averaged F1 scores, and 95% confidence intervals were calculated to quantify uncertainty. Fine-tuned BioClinicalBERT models achieved near-perfect performance, with macro F1 scores >=0.998 on the internal test set. External validation confirmed robustness (macro F1=0.966), outperforming conventional machine learning, general-domain BERT models, and various decoder-only large language models. NLP models, particularly fine-tuned clinical variants like BioClinicalBERT, offer a highly accurate and scalable solution for overdose death classification from free-text reports. These methods can significantly accelerate surveillance workflows, overcoming the limitations of manual ICD-10 coding and supporting near real-time detection of emerging substance use trends.
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- Health & Medicine > Therapeutic Area > Psychiatry/Psychology > Addiction Disorder (1.00)
- Health & Medicine > Pharmaceuticals & Biotechnology (1.00)
Structured Reinforcement Learning for Media Streaming at the Wireless Edge
Bura, Archana, Bobbili, Sarat Chandra, Rameshkumar, Shreyas, Rengarajan, Desik, Kalathil, Dileep, Shakkottai, Srinivas
Media streaming is the dominant application over wireless edge (access) networks. The increasing softwarization of such networks has led to efforts at intelligent control, wherein application-specific actions may be dynamically taken to enhance the user experience. The goal of this work is to develop and demonstrate learning-based policies for optimal decision making to determine which clients to dynamically prioritize in a video streaming setting. We formulate the policy design question as a constrained Markov decision problem (CMDP), and observe that by using a Lagrangian relaxation we can decompose it into single-client problems. Further, the optimal policy takes a threshold form in the video buffer length, which enables us to design an efficient constrained reinforcement learning (CRL) algorithm to learn it. Specifically, we show that a natural policy gradient (NPG) based algorithm that is derived using the structure of our problem converges to the globally optimal policy. We then develop a simulation environment for training, and a real-world intelligent controller attached to a WiFi access point for evaluation. We empirically show that the structured learning approach enables fast learning. Furthermore, such a structured policy can be easily deployed due to low computational complexity, leading to policy execution taking only about 15$\mu$s. Using YouTube streaming experiments in a resource constrained scenario, we demonstrate that the CRL approach can increase quality of experience (QOE) by over 30\%.
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AI4OPT: AI Institute for Advances in Optimization
Van Hentenryck, Pascal, Dalmeijer, Kevin
This article is a short introduction to AI4OPT, the NSF AI Institute for Advances in Optimization. AI4OPT fuses AI and Optimization, inspired by end-use cases in supply chains, energy systems, chip design and manufacturing, and sustainable food systems. AI4OPT also applies its "teaching the teachers" philosophy to provide longitudinal educational pathways in AI for engineering.
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- Education > Educational Setting > K-12 Education (0.48)
Data Engineer Intern (Remote)
Trace3 is a leading Transformative IT Authority, providing unique technology solutions and consulting services to our clients. Equipped with elite engineering and dynamic innovation, we empower IT executives and their organizations to achieve competitive advantage through a process of Integrate, Automate, Innovate. Our culture at Trace3 embodies the spirit of a startup with the advantage of a scalable business. Employees can grow their career and have fun while doing it! We employ more than 1,000 people all over the United States.
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Data Engineer Intern
Trace3 is a leading Transformative IT Authority, providing unique technology solutions and consulting services to our clients. Equipped with elite engineering and dynamic innovation, we empower IT executives and their organizations to achieve competitive advantage through a process of Integrate, Automate, Innovate. Our culture at Trace3 embodies the spirit of a startup with the advantage of a scalable business. Employees can grow their career and have fun while doing it! We employ more than 1,000 people all over the United States.
- North America > United States > Texas > Duval County > San Diego (0.07)
- North America > United States > Indiana > Marion County > Indianapolis (0.07)
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